"...Between any neurons, between the axon of one neuron and the dendrite of another, there's a tiny gap. The gap could be about one ten-thousandths of a millimeter wide. This infinitesimal gap — and this gap is known as a synapse — and what happens is when a neuron fires, an axon sends chemicals shooting through the gap. These chemicals are known as neurotransmitters and they affect the dendrites. So, neurons communicate to one another chemically. Again, the chemicals could excite the other neuron (excitatory) bring up the chances it will fire, or inhibit the other neuron (inhibitory).
Now, neurotransmitters become interesting because a lot of psychopharmacology, both of the medical sort and the recreational sort, consists of fiddling with neurotransmitters and so you could see this through some examples. There are two sorts of ways you could fiddle with neurotransmitters, and correspondingly two sorts of drugs. There are agonists.
And what an agonist does is increases the effect of neurotransmitters, either by making more neurotransmitters or stopping the cleanup of neurotransmitters, or in some cases by faking a neurotransmitter, by mimicking its effects. Then, there are antagonists that slow down the amount of neurotransmitters, either because they destroy neurotransmitters or they make it hard to create more. Or in some cases they go to the dendrite of the neuron and they kind of put a paste over it so that the neurotransmitters can't connect. And it's through these clever ways that neurons can affect your mental life."
© Paul Bloom
Yale Lectures on Introduction to Psychology, 2007
Now, neurotransmitters become interesting because a lot of psychopharmacology, both of the medical sort and the recreational sort, consists of fiddling with neurotransmitters and so you could see this through some examples. There are two sorts of ways you could fiddle with neurotransmitters, and correspondingly two sorts of drugs. There are agonists.
And what an agonist does is increases the effect of neurotransmitters, either by making more neurotransmitters or stopping the cleanup of neurotransmitters, or in some cases by faking a neurotransmitter, by mimicking its effects. Then, there are antagonists that slow down the amount of neurotransmitters, either because they destroy neurotransmitters or they make it hard to create more. Or in some cases they go to the dendrite of the neuron and they kind of put a paste over it so that the neurotransmitters can't connect. And it's through these clever ways that neurons can affect your mental life."
© Paul Bloom
Yale Lectures on Introduction to Psychology, 2007
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